Website outages and system releases
The European Medicines Agency (EMA) makes upgrades to this website and the Clinical Trials Information System (CTIS) from time to time, to improve user experience.
During these times, CTIS and this website may be temporarily unavailable or not work optimally.
You can see when we are planning the next outage below. Registered users can also see notice of any planned interruptions in EMA Service Desk.
Below you can find the full release notes and a list of any outstanding issues and proposed workarounds for these issues.
Some functionalities within CTIS rely on other systems which are also maintained by EMA. Upgrades and related work on any of these systems can affect CTIS users’ ability to perform some actions. You can see when we are planning the next maintenance on these systems below.
Planned system interruptions
Users are advised to avoid using CTIS or this website during the regular maintenance windows:
- Tuesdays and Thursdays, from 18:00 to 21:00 Amsterdam time
- Every first Saturday of the month, from 10:00 to 14:00 Amsterdam time
The time zone used in CTIS is Central European Time (CET). All due dates and deadlines are displayed in CET despite the daylight-saving time change taking place in Europe on 26 March 2023.
Unplanned system interruptions
If CTIS is unexpectedly down outside of the above downtime windows, users can consult EMA's User support Service landing page for further information.
About release notes
These documents outline the latest updates
to the
CTIS system, including the secure Sponsor and Authority workspaces, and to the
Clinical
Trials website. Updates may include improvements to existing features and
functionality,
the addition of new features and functionality and technical improvements.
Release notes February 2025
List of known issues and proposed workarounds:
Release notes December 2024
Release notes November 2024
List of known issues and proposed workarounds:
Release notes October 2024
Release notes September 2024
Release notes v1.0.44.0 (PDF, in English)
CTIS Release Notes public portal v2.1.0.pdf (PDF, in English)
List of known issues and proposed workarounds:
Release notes August 2024
Release notes July 2024
List of known issues and proposed workarounds:
Release notes June 2024
Release notes May 2024
List of known issues and proposed workarounds:
Release notes April 2024
Release notes February 2024
Release notes January 2024
Release notes December 2023
Release notes v1.0.33.0 (PDF, in English)
These documents outline the latest updates to the CTIS system, including the secure Sponsor and Authority workspaces, and to the Clinical
Trials website. Updates may include improvements to existing features and
functionality,
the addition of new features and functionality and technical improvements.
Release notes October 2023
Release notes September 2023
Release notes July 2023
Release notes May 2023
Release notes March 2023
Release notes v1.0.16.0 (PDF, in English)
Release notes v1.0.18.0 (PDF, in English)
Release notes v1.0.19.0 (PDF, in English)
Release notes v1.0.20.0 (PDF, in English)
List of known issues and proposed workarounds:
- for CTIS sponsor workspace users v1.0.16.0 (PDF, in English)
- for CTIS authority workspace users v1.0.16.0 (PDF, in English)
- for CTIS sponsor workspace users v1.0.18.0 (PDF, in English)
- for CTIS authority workspace users v1.0.18.0 (PDF, in English)
- for CTIS sponsor workspace users v1.0.20.0 (PDF, in English)
- for CTIS authority workspace users v1.0.20.0 (PDF, in English)
Release notes February 2023
Release notes January 2023
Release notes December 2022
List of known issues and proposed workarounds:
Release notes November 2022
Release notes October 2022
List of known issues and proposed workarounds:
Release notes September 2022
List of known issues and proposed workarounds:
Release notes July 2022
List of known issues and proposed workarounds:
Release notes May 2022
List of known issues and proposed workarounds:
Release notes January 2022
This document outlines the latest updates to the CTIS system, including the secure Sponsor and Authority workspaces, and to the Clinical Trials website. Updates may include improvements to existing features and functionality, the addition of new features and functionality and technical improvements, such as improvements to system performance.
List of known issues and proposed workarounds:
Support and training
